The answer would NO, scanned images, or any image on a computer can be used if the quality is good enough. But the bigger the lenticular image you want, the bigger the original artwork needs to be.

All Artwork must be saved in layers.
Here are some tips that may help:
a Keep one simple background throughout the animation.
b Avoid Red to Green, Blue to Yellow, Black to White.
c Image is animated depending on flow of people - left/ight, right/left, up/down.
d Where is this image going?
e How far away is the average viewer?
f Avoid strong vertical or horizontal lines.
g Scenes should have good colour saturation.
h Slight movement is more effective than too much
i Original artwork works better if it has perspective elements already like shadows, embossing etc.
j You can combine effects.
Additional Design Tips - Flip and Animotion - produces visual effects of motion, movement, morphing and contrast to retain brand awareness or marketing messages.
a On large scale they are most effective at viewing distances of 1 - 3 metres on a 30lpi lens, but 4m or greater on a 15lpi lens.
b 2 images is extremely effective, but is more dramatic or subtle change is required, up to 6 flips should be considered
c Don't use small text and fine diagonal keylines as this will be obscured by the lens.
d Attempt to keep dominant colours similar in hue and strength.
e Artwork should be saved and supplied in layers ideally in Adobe Photoshop.f All files should be in CMYK.
g Include ALL elements, all layers and attachments, including fonts.
h Supply a print-out or marked-up visual with your definition of the focal point, the layer or items which we will place the central layer.